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Test Code FNTSX Fentanyl and Metabolite, Chain of Custody, Serum

Useful For

Monitoring fentanyl therapy


Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the rights of the individual contributing the specimen by demonstrating that it was under the control of personnel involved with testing the specimen at all times; this control implies that the opportunity for specimen tampering would be limited.

Additional Tests

Test ID Reporting Name Available Separately Always Performed
COCH Chain of Custody Processing No Yes

Reporting Name

Fentanyl and metabolite, CoC, S

Specimen Type

Serum Red

Specimen Required

Supplies: Chain-of-Custody Kit (T282)

Collection Container/Tube: Red top (Serum gel/SST are not acceptable); Chain-of-Custody Kit containing the specimen seals and documentation required.

Submission Container/Tube: Plastic vial

Specimen Volume: 2.3 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial within 2 hours of collection.

Specimen Minimum Volume

1.25 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Frozen (preferred) 14 days
  Refrigerated  14 days
  Ambient  72 hours

Day(s) Performed

Monday, Wednesday

Report Available

2 to 7 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information


G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FNTSX Fentanyl and metabolite, CoC, S 81275-0


Result ID Test Result Name Result LOINC Value
36302 Norfentanyl 11074-2
36303 Fentanyl 3636-8
36304 Chain of Custody 77202-0

Reference Values

Not applicable

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)


1. Chain of Custody Request is included in the Chain-of-Custody Kit (T282).

2. If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.