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Test Code SAT24 Supersaturation Profile, 24 Hour, Urine

Useful For

Diagnosis and management of patients with renal lithiasis:

-Predicting the likely composition of the stone, in patients who have a radiopaque stone, for whom stone analysis is not available. This may help in designing a treatment program.

 

Aiding in identification of specific risk factors for stones using a 24-hour urine collection

 

Monitoring the effectiveness of therapy by confirming that the crystallization potential has indeed decreased

 

Evaluation of kidney excretion of acid and urine pH

 

Estimation of a patient's protein intake

Profile Information

Test ID Reporting Name Available Separately Always Performed
SUPST Supersaturation, U No Yes
NAUP Sodium, U Yes, (order NAU) Yes
KUP Potassium, U Yes, (order KUR) Yes
CALCP Calcium, U Yes, (order CALU) Yes
MAGP Magnesium, U Yes, (order MAGU) Yes
CLUP Chloride, U Yes, (order CLU) Yes
POUP Phosphorus, U Yes, (order POU) Yes
SULFP Sulfate, 24 Hr, U Yes, (order SULFU) Yes
CITP Citrate Excretion, U Yes, (order CITR) Yes
OXUP Oxalate, U Yes, (order OXU) Yes
UPHP pH, U Yes, (order PHU_) Yes
URCP Uric Acid, U Yes, (order URCU) Yes
CTUP Creatinine, U Yes, (order CTU) Yes
UOSMP Osmolality Yes, (order UOSMU) Yes
AMMP Ammonium, 24 Hr, U Yes, (order AMMO) Yes
UNP Urea Nitrogen, U No Yes
PCTR Protein Catabolic Rate, U No Yes
DEMO4 Patient Demographics No Yes

Method Name

AMMP, CITP, OXUP: Enzymatic

USOMP: Freezing Point Depression

SULFP: High-Performance Ion Chromatography (HPIC)

CALCP: Photometric

MAGP: Colorimetric Endpoint Assay

POUP: Molybdic Acid

UPHP: pH Meter

NAUP, KUP, CLUP: Potentiometric, Indirect Ion-Selective Electrode (ISE)

CTUP: Enzymatic Colorimetric Assay

URCP: Uricase

UNP: Kinetic UV Assay

Reporting Name

Supersaturation, U

Specimen Type

Urine


Ordering Guidance


X-ray dyes and contrast media will affect uric acid test results.

-If a kidney X-ray with dye or computerized tomography scan with contrast has been performed, patient should wait a minimum of 1 day before starting collection.

-If a cholangiography (bile duct X-ray) has performed, patient should wait 7 days before starting collection.

-Urine must be collected before tablets have been taken for gallbladder X-ray, otherwise patient should wait 7 days before starting collection.



Necessary Information


1. Twenty-four hour volume is required.

2. Patient's height in centimeters and weight in kilograms are required if patient is younger than 18 years.



Specimen Required


Supplies: Diazolidinyl Urea (Germall), 5.0 mL (T822)

Collection Container/Tube: 24-hour graduated urine container with no metal cap or glued insert

Submission Container/Tube: Plastic, 60-mL urine bottle

Specimen Volume: 35 mL

Collection Instructions:

1. Collect urine for 24 hours.

2. Add 5 mL of diazolidinyl urea as preservative at start of collection or refrigerate specimen during as well as after collection.

3. Specimen pH should be between 4.5 and 8 and will stay in this range if kept refrigerated. Specimens with pH >8 indicate bacterial contamination, and testing will be cancelled. Do not attempt to adjust pH as it will adversely affect results.

Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.


Specimen Minimum Volume

25 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated 14 days

Reference Values

SUPERSATURATION REFERENCE MEANS (Delta G: DG)

Calcium oxalate: 1.77 DG

Brushite: 0.21 DG

Hydroxyapatite: 3.96 DG

Uric acid: 1.04 DG

Sodium urate: 1.76 DG

 

INDIVIDUAL URINE ANALYTES

 

OSMOLALITY

0-11 months: 50-750 mOsm/kg

≥12 months: 150-1,150 mOsm/kg

 

pH

4.5 to 8.0

 

ALL REFERENCE RANGES BELOW ARE BASED ON 24-HOUR COLLECTIONS.

 

SODIUM

≥18 years: 22-328 mmol/24 h

Reference values have not been established for patients who are younger than 18 years of age.

 

POTASSIUM

≥18 years: 16-105 mmol/24 h

Reference values have not been established for patients who are younger than 18 years of age.

 

CALCIUM

Males: <250 mg/24 h

Females: <200 mg/24 h

Reference values have not been established for patients who are younger than 18 years of age.

 

MAGNESIUM

≥18 years: 51-269 mg/24 h

Reference values have not been established for patients who are younger than 18 years of age.

 

CHLORIDE

≥18 years: 34-286 mmol/24 h

Reference values have not been established for patients who are younger than 18 years of age.

 

PHOSPHORUS

≥18 years: 226-1,797 mg/24h

Reference values have not been established for patients who are younger than 18 years of age.

 

SULFATE

7-47 mmol/24 h

 

CITRATE EXCRETION

0-19 years: Not established

20 years: 150-1,191 mg/24 h

21 years: 157-1,191 mg/24 h

22 years: 164-1,191 mg/24 h

23 years: 171-1,191 mg/24 h

24 years: 178-1,191 mg/24 h

25 years: 186-1,191 mg/24 h

26 years: 193-1,191 mg/24 h

27 years: 200-1,191 mg/24 h

28 years: 207-1,191 mg/24 h

29 years: 214-1,191 mg/24 h

30 years: 221-1,191 mg/24 h

31 years: 228-1,191 mg/24 h

32 years: 235-1,191 mg/24 h

33 years: 242-1,191 mg/24 h

34 years: 250-1,191 mg/24 h

35 years: 257-1,191 mg/24 h

36 years: 264-1,191 mg/24 h

37 years: 271-1,191 mg/24 h

38 years: 278-1,191 mg/24 h

39 years: 285-1,191 mg/24 h

40 years: 292-1,191 mg/24 h

41 years: 299-1,191 mg/24 h

42 years: 306-1,191 mg/24 h

43 years: 314-1,191 mg/24 h

44 years: 321-1,191 mg/24 h

45 years: 328-1,191 mg/24 h

46 years: 335-1,191 mg/24 h

47 years: 342-1,191 mg/24 h

48 years: 349-1,191 mg/24 h

49 years: 356-1,191 mg/24 h

50 years: 363-1,191 mg/24 h

51 years: 370-1,191 mg/24 h

52 years: 378-1,191 mg/24 h

53 years: 385-1,191 mg/24 h

54 years: 392-1,191 mg/24 h

55 years: 399-1,191 mg/24 h

56 years: 406-1,191 mg/24 h

57 years: 413-1,191 mg/24 h

58 years: 420-1,191 mg/24 h

59 years: 427-1,191 mg/24 h

60 years: 434-1,191 mg/24 h

>60 years: Not established 

OXALATE

0.11-0.46 mmol/24 h

9.7-40.5 mg/24 h

Reference values have not been established for patients who are younger than 16 years of age.

 

URIC ACID

Male: ≥18 years: 200-1,000 mg/24 h

Female: ≥18 years: 250-750 mg/24 h

Reference values have not been established for patients who are younger than 18 years of age.

 

CREATININE

Male: ≥18 years: 930-2,955 mg/24 h

Female: ≥18 years: 603-1,783 mg/24 h

Reference values have not been established for patients who are younger than 18 years of age.

 

AMMONIUM

15-56 mmol/24 h

Reference values have not been established for patients younger than 18 years and older than 77 years of age.

 

UREA NITROGEN

≥18 years: 7-42 g/24 h

Reference values have not been established for patients who are younger than 18 years of age.

 

PROTEIN CATABOLIC RATE

56-125 g/24 h

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

82340-Calcium

82436-Chloride

82507-Citrate excretion

82570-Creatinine

83735-Magnesium

83935-Osmolality

83945-Oxalate

83986-pH

84105-Phosphorus

84133-Potassium

84300-Sodium

84392-Sulfate

84560-Uric acid

82140-Ammonium

84540-Urea Nitrogen

LOINC Code Information

Test ID Test Order Name Order LOINC Value
SAT24 Supersaturation, U 81232-1

 

Result ID Test Result Name Result LOINC Value
CAL24 Calcium, 24 Hr, U 6874-2
UN24 Urea Nitrogen, U 3096-5
MAG24 Magnesium, 24 Hr, U 24447-5
BSA Patient Surface Area 8277-6
AMM24 Ammonium, 24 Hr, U 25308-8
PCTR Protein Catabolic Rate, U 93746-6
UPHU pH, U 27378-9
URACI Uric Acid, U 3087-4
UOSMP Osmolality 2694-8
CITRE Citrate Excretion, U 6687-8
CL24 Chloride, U 2079-2
CRETU Creatinine, U 2162-6
K24U Potassium, U 2829-0
NA24 Sodium, U 2956-1
OXLT Oxalate, U (mmol/24 h) 14862-7
PHS_U Phosphorus, U 2779-7
SULF_ Sulfate, 24 Hr, U 26889-6
21041 Calcium Oxalate Crystal 81623-1
21042 Brushite Crystal In Process
OXU2 Oxalate, mg/24 h 2701-1
HT5 Height (cm) 3137-7
WT4 Weight (kg) 29463-7
21043 Hydroxyapatite Crystal 81622-3
21044 Uric Acid Crystal In Process
21045 Sodium Urate Crystal In Process
CLDUR Collection Duration 13362-9
VL38 Volume 3167-4
21060 Interpretation 69051-1

Urine Preservative Collection Options

Note: The addition of preservative or application of temperature controls must occur at the beginning of the collection.

Ambient

No

Refrigerate

OK

Frozen

No

50% Acetic Acid

No

Boric Acid

No

Diazolidinyl Urea

Preferred

6M Hydrochloric Acid

No

6M Nitric Acid

No

Sodium Carbonate

No

Thymol

No

Toluene

No

 

Forms

If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

Day(s) Performed

Monday through Friday

Report Available

2 to 5 days