Test Code COWB Cobalt, Blood
Ordering Guidance
This test should not be ordered to assess vitamin B12 activity. For that assessment see B12 / Vitamin B12 Assay, Serum or ACASM / Pernicious Anemia Cascade, Serum.
Specimen Required
Patient Preparation: High concentrations of gadolinium and iodine are known to potentially interfere with most inductively coupled plasma mass spectrometry-based metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
Supplies: Metal Free EDTA 3 mL Tube (T989)
Container/Tube: Royal blue-top BD vacutainer with EDTA blood collection tube (3 mL) (BD catalog no. 367777) (T989)
Specimen Volume: 1 mL
Collection Instructions:
1. See Metals Analysis Specimen Collection and Transport for complete instructions
2. Send whole blood specimen in original tube. Do not aliquot.
Useful For
Monitoring exposure to cobalt using whole blood specimens
Monitoring metallic prosthetic implant wear
This test is not useful for assessment of vitamin B12 activity.
Special Instructions
Method Name
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)
Reporting Name
Cobalt, BSpecimen Type
Whole bloodSpecimen Minimum Volume
0.3 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Whole blood | Refrigerated (preferred) | 28 days | |
Ambient | 28 days | ||
Frozen | 28 days |
Reference Values
0-17 years: Not established
≥18 years: <1.0 ng/mL
Day(s) Performed
Tuesday, Wednesday, Friday
Report Available
1 to 4 daysPerforming Laboratory

Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
83018
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
COWB | Cobalt, B | 5625-9 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
60355 | Cobalt, B | 5625-9 |