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Test Code CRCL Creatinine Clearance, Plasma or Serum and Urine

Methodology

Kinetic Jaffe Reaction, Modified

Performing Laboratory

Aspen Valley Hospital

Specimen Requirements

Plasma or serum and urine are required for this test. Plasma or serum specimen should be obtained sometime during the 24-hour urine collection or within 48 hours of the 24-hour urine collection.

 

Preferred:

Plasma

Container/Tube:  Light green-top (lithium heparin gel) tube(s)

Specimen:  1 mL (minimum volume:  0.5 mL) of lithium heparin plasma

Transport Temperature:  Ambient

Collection Instructions:  Spin down immediately and send entire tube to laboratory. If there is a delay in transport of >8 hours, send specimen refrigerated.

Note:  1. Patient’s height and weight are required on request form for calculation of the creatinine clearance.

2. Indicate plasma on request form.
3. Label specimen appropriately (plasma).

 

Alternate:

Serum

Container/Tube:  Gold-top serum gel tube(s) - Plain, red-top tube is also acceptable.

Specimen:  1 mL (minimum volume:  0.5 mL) of serum

Transport Temperature:  Ambient

Collection Instructions:  Allow specimen to clot for approximately 10 minutes and spin down. If drawing gold-top serum gel tube, send entire tube to laboratory. If drawing plain, red-top tube, remove serum and place in separate plastic vial. If there is a delay in transport of >8 hours, send specimen refrigerated.

Note:  1. Patient’s height and weight are required on request form for calculation of the creatinine clearance.

2. Indicate serum on request form.
3. Label specimen appropriately (serum).

 

Urine

Send entire 24-hour urine collection in a plastic urine container. No preservative. Refrigerate specimen during collection, and send specimen refrigerated.

Note:  1. Patient’s height and weight and starting and ending times of collection are required on request form for processing.
2. Follow instructions in “Urine Collection” in “Special Instructions.”

Reference Values

CREATININE, PLASMA OR SERUM

0.6-1.3 mg/dL

CREATININE CLEARANCE

Males:  85-125 mL/min

Females

Non-pregnant:  75-115 mL/min

Pregnant:  >100 mL/min

CREATININE, URINE

0.6-2.5 g/24 hours

Day(s) Test Set Up

Monday through Sunday

Test Classification and CPT Coding

81050 - urine timed measurement

82575 - creatinine clearance

Special Instructions