Sign in →

Test Code HBAGP Hepatitis B Surface Antigen Prenatal, Serum

Reporting Name

HBs Antigen Prenatal, S

Useful For

Diagnosis of acute, recent, or chronic hepatitis B infection (HBV)


Determination of chronic HBV infection status


Screening pregnant women for evidence of chronic HBV (or hepatitis B carrier state) to identify neonates who are at high risk of acquiring HBV at birth


This test should not be used as a screening or confirmatory test for blood donor specimens.


This test is not useful for diagnosis of hepatitis B during the “window period" of acute HBV infection (ie, after disappearance of hepatitis B surface antigen and prior to appearance of hepatitis B surface antibody).


Reflex Tests

Test ID Reporting Name Available Separately Always Performed
HBNTP HBs Ag Confirmation Prenatal, S No No

Testing Algorithm

If hepatitis B surface antigen (HBsAg) prenatal is reactive, then HBsAg confirmation will be performed at an additional charge.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum SST

Ordering Guidance

This test should not be used to test symptomatic individuals who may or may not have risk factors for hepatitis B virus (HBV) infection. For testing such individuals, order HBAG / Hepatitis B Surface Antigen, Serum.


This test should not be used to screen or test asymptomatic, nonpregnant individuals with or without risk factors for HBV infection. For testing such patients, order HBGSN / Hepatitis B Surface Antigen Screen, Serum.


This test is not intended for testing cadaver or grossly hemolyzed specimens. For testing such patients, order HBGCD / Hepatitis B Surface Antigen for Cadaveric or Hemolyzed Specimens, Serum, which is US Food and Drug Administration-approved for testing on these sources.

Additional Testing Requirements

Testing for acute hepatitis B virus (HBV) infection should also include HBIM / Hepatitis B Core Antibody, IgM, Serum, as during the acute HBV infection "window period," hepatitis B surface (HBs) antigen and HBs antibody may not be detected.

Necessary Information

1. Date of collection is required.

2. Indicate if specimens are from autopsy/cadaver or hemolyzed sources so that the proper FDA-licensed assay can be performed.

Specimen Required

Collection Container/Tube: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Collection Instructions:

1. Centrifuge blood collection tube per collection tube manufacturer's instructions (eg, centrifuge and aliquot within 2 hours of collection for BD Vacutainer tubes).

2. Aliquot serum into plastic vial.

Specimen Minimum Volume

0.6 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum SST Frozen (preferred) 28 days
  Refrigerated  7 days
  Ambient  24 hours

Special Instructions

Reference Values


See Viral Hepatitis Serologic Profiles.

Day(s) Performed

Monday through Sunday

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information


87341 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HBAGP HBs Antigen Prenatal, S 5196-1


Result ID Test Result Name Result LOINC Value
HBSAP HBs Antigen Prenatal, S 5196-1

Report Available

Same day/1 to 2 days

Method Name

Chemiluminescence Immunoassay (CIA)


If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.