Test Code PLAIF Phospholipase A2 Receptor (PLA2R), Renal Biopsy
Ordering Guidance
This test will report as negative or positive for autoantibodies to phospholipase A2 receptor.
If additional interpretation/analysis is needed, request PATHC / Pathology Consultation along with this test and send: 1) the corresponding renal pathology light microscopy and immunofluorescence (IF) slides (or IF images on a CD); 2) electron microscopy images (prints or CD); and 3) the pathology report.
Shipping Instructions
1. Advise shipping frozen specimens (unstained slides or tissue block) in Styrofoam transportation coolers filled with dry ice to ensure specimens are received at required specimen stability temperature.
2. Attach the green "Attention Pathology" address label (T498) to the outside of the transport container before putting into the courier mailer.
Necessary Information
A pathology/diagnostic report is required.
Specimen Required
Submit only 1 of the following specimens:
Preferred:
Specimen Type: Unstained slides (unfixed)
Source: Kidney tissue
Slides: 2 Slides
Collection Instructions: 2 frozen tissue unstained positively charged glass slides (25- x 75- x 1-mm) per test ordered; sections 4-microns thick, centered on the slide, and submitted on dry ice.
Acceptable:
Specimen Type: Unfixed tissue block (O.C.T)
Source: Kidney tissue
Specimen Volume: Entire specimen
Collection Instructions:
1. Embed in O.C.T. compound.
2. Freeze specimen and ship on dry ice.
Acceptable:
Specimen Type: Wet tissue
Source: Kidney tissue
Supplies: Renal Biopsy Kit (T231)
Container/Tube: Renal Biopsy Kit, Zeus/Michel's
Specimen Volume: Entire specimen
Collection Instructions: Collect specimens according to the instructions in Renal Biopsy Procedure for Handling Tissue for Light Microscopy, Immunofluorescent Histology, and Electron Microscopy.
Additional Information: If standard immunoglobulin and complement immunofluorescence have already been performed, submit the residual frozen tissue (must contain glomeruli) on dry ice.
Forms
1. Renal Biopsy Patient Information
2. If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.
Special Instructions
Method Name
Immunofluorescence
Reporting Name
PLA2R ImmunofluorescenceSpecimen Type
SpecialSpecimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Special | Frozen |
Day(s) Performed
Monday through Friday
Report Available
1 to 2 daysPerforming Laboratory

Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
88346-primary IF
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
PLAIF | PLA2R Immunofluorescence | In Process |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
71225 | Interpretation | 59465-5 |
71226 | Participated in the Interpretation | No LOINC Needed |
71227 | Report electronically signed by | 19139-5 |
71228 | Addendum | 35265-8 |
71229 | Gross Description | 22634-0 |
71230 | Material Received | 81178-6 |
71617 | Disclaimer | 62364-5 |
71847 | Case Number | 80398-1 |
Specimen Minimum Volume
See Specimen Required
Reference Values
An interpretive report will be provided.