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Test Code PLAIF Phospholipase A2 Receptor (PLA2R), Renal Biopsy


Ordering Guidance


This test will report as negative or positive for autoantibodies to phospholipase A2 receptor.

 

If additional interpretation/analysis is needed, request PATHC / Pathology Consultation along with this test and send: 1) the corresponding renal pathology light microscopy and immunofluorescence (IF) slides (or IF images on a CD); 2) electron microscopy images (prints or CD); and 3) the pathology report.



Shipping Instructions


1. Advise shipping frozen specimens (unstained slides or tissue block) in Styrofoam transportation coolers filled with dry ice to ensure specimens are received at required specimen stability temperature.

2. Attach the green "Attention Pathology" address label (T498) to the outside of the transport container before putting into the courier mailer.



Necessary Information


A pathology/diagnostic report is required.



Specimen Required


Submit only 1 of the following specimens:

 

Preferred:

Specimen Type: Unstained slides (unfixed)

Source: Kidney tissue

Slides: 2 Slides

Collection Instructions: 2 frozen tissue unstained positively charged glass slides (25- x 75- x 1-mm) per test ordered; sections 4-microns thick, centered on the slide, and submitted on dry ice.

 

Acceptable:

Specimen Type: Unfixed tissue block (O.C.T)

Source: Kidney tissue

Specimen Volume: Entire specimen

Collection Instructions:

1. Embed in O.C.T. compound.

2. Freeze specimen and ship on dry ice.

 

Acceptable:

Specimen Type: Wet tissue

Source: Kidney tissue

Supplies: Renal Biopsy Kit (T231)

Container/Tube: Renal Biopsy Kit, Zeus/Michel's

Specimen Volume: Entire specimen

Collection Instructions: Collect specimens according to the instructions in Renal Biopsy Procedure for Handling Tissue for Light Microscopy, Immunofluorescent Histology, and Electron Microscopy.

Additional Information: If standard immunoglobulin and complement immunofluorescence have already been performed, submit the residual frozen tissue (must contain glomeruli) on dry ice.


Forms

1. Renal Biopsy Patient Information

2. If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.

Method Name

Immunofluorescence

Reporting Name

PLA2R Immunofluorescence

Specimen Type

Special

Specimen Stability Information

Specimen Type Temperature Time Special Container
Special Frozen

Day(s) Performed

Monday through Friday

Report Available

1 to 2 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

88346-primary IF

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PLAIF PLA2R Immunofluorescence In Process

 

Result ID Test Result Name Result LOINC Value
71225 Interpretation 59465-5
71226 Participated in the Interpretation No LOINC Needed
71227 Report electronically signed by 19139-5
71228 Addendum 35265-8
71229 Gross Description 22634-0
71230 Material Received 81178-6
71617 Disclaimer 62364-5
71847 Case Number 80398-1

Specimen Minimum Volume

See Specimen Required

Reference Values

An interpretive report will be provided.