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Test Code VLTS Volatile Screen, Serum

Reporting Name

Volatile Scrn, S

Useful For

Detection and quantitation of acetone, methanol, isopropanol, and ethanol in serum


Quantification of the concentration of ethanol in serum correlates with degree of intoxication


Evaluation of toxicity to the measured volatile substances

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type


Additional Testing Requirements

If measurement of ethylene glycol is also needed, order ETGL / Ethylene Glycol, Serum in addition to this test.

Specimen Required


Preferred: Serum gel

Acceptable: Red top

Specimen Volume: Full tube

Collection Instructions:

1. Patient arm must be cleansed with water only.

2. Avoid exposure of specimen to atmosphere.

3. Do not aliquot serum gel tubes.

4. Centrifuge red-top tubes and aliquot serum in plastic vial within 2 hours of collection. Send serum aliquot refrigerated.

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  28 days
  Ambient  24 hours

Reference Values


Not detected (Positive results are quantitated.)

Toxic concentration: ≥10 mg/dL



Not detected (Positive results are quantitated.)

Toxic concentration: ≥400 mg/dL



Not detected (Positive results are quantitated.)

Toxic concentration: ≥10 mg/dL



Not detected (Positive results are quantitated.)

Toxic concentration: ≥10 mg/dL

Day(s) Performed

Monday through Saturday

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information


G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
VLTS Volatile Scrn, S 50025-6


Result ID Test Result Name Result LOINC Value
8632 Volatile Scrn, S 32044-0
30917 Methanol, S 5693-7
30918 Ethanol, S 5643-2
30919 Acetone, S 5568-1
30920 Isopropanol, S 5669-7
34376 Chain of Custody 77202-0

Report Available

2 to 3 days

Method Name

Headspace Gas Chromatography-Flame Ionization Detector (HSGC-FID)

Testing Algorithm

This test includes analysis for methanol, ethanol, isopropanol, and acetone.


If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.