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Test Code VORI Voriconazole, Serum

Reporting Name

Voriconazole, S

Useful For

Monitoring trough levels of voriconazole is suggested for:

-Individuals with reduced liver function

-Individuals with cytochrome P450 (CYP) 2C19 alterations associated with poor metabolic function

-Patients taking other medications that affect CYP2C19 activity

-Patients experiencing potential toxicity

 

Monitoring trough levels may be reasonable in patients who are not responding optimally or have drug interactions that may decrease voriconazole levels or to ensure adequate oral absorption

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum Red


Specimen Required


Collection Container/Tube: Red top (serum gel/SST not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial within 2 hours of collection.


Specimen Minimum Volume

0.6 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reference Values

1.0-5.5 mcg/mL

Trough level (ie, immediately before next dose) monitoring is recommended.

Day(s) Performed

Monday through Sunday

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

80285

LOINC Code Information

Test ID Test Order Name Order LOINC Value
VORI Voriconazole, S 38370-3

 

Result ID Test Result Name Result LOINC Value
88698 Voriconazole, S 38370-3

Report Available

Same day/1 to 2 days

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)